Huperzine A Alzheimer's Information

Huperzine A (Huperzia serrata) for Dementia, Memory Loss, Senility, Alzheimer's Mental Decline. Huperzine A is a good alternative to Aricept (donepezil), Exelon (rivastigmine) and Reminyl (galantamine) - cholinesterase inhibitor drugs.

Being a care giver for an Alzheimer's or dementia patient is no picnic. It is terrible to see a loved one start to lose their mind and depend on you for everything, including assistance with activities of daily living: hygiene, getting dressed, combing their hair, etc. The longer they stay mentally alert, the easier and safer it is to care for them.

This is why we are offering Huperzine A - to improve the memories and quality of life for dementia patients.

Huperzine A

Huperzine A is a plant extract derived from Chinese Club Moss. It has been used for centuries in Chinese Traditional Medicine to rejuvenate memory in the elderly. Technically, this "memory moss" is a better brain booster than Aricept and Cognex, two prescription drugs prescribed for reversing memory deficits with Alzheimer's patients.

Huperzine A also helps victims of TIAs (mini-strokes) who suffer from multi-infarct dementia. Unlike prescription medication for Alzheimers, it does not have liver toxicity. In the US, it is being tested in clinical trials for the treatment of Alzheimer�s and age-related cognitive decline (ARCD)� a term which covers variety of memory loss problems.

Researchers believe Huperzine works by protecting a key neurotransmitter called acetylcholine. Acetylcholine is released at the synapse (gap) between two nerve cells and stimulates the impulse from one brain cell to the next. An enzyme called acetylcholine esterase (AchE) then destroys the acetylcholine and terminates the nerve signal (after it�s been transmitted).

Scientists believe that in some memory disorders the acetylcholine is destroyed too soon, and the nerve impulse is too weak to be received � an undesirable effect that may also play a role in normal, age-related memory deficits. Studies show Huperzine inhibits AchE, the enzyme that destroys acetylcholine, and thereby strengthens or lengthens the duration of the nerve impulse. This alone could make the difference between vaguely remembering something and clear recollection.

In China, two double blind clinical studies demonstrated that Huperzine A is both safe and effective for long-term treatment of Alzheimer�s dementia. In a double-blind trial with a group of 56 patients suffering from senile dementia as well as a group of 104 patients with senile and pre-senile memory loss, Huperzine A was demonstrated to be effective for improving memory.

Huperzine A has been proven superior to drugs licensed for the treatment of Alzheimer�s, including the leading anticholinesterase drugs physostigmine and tacrine. Huperzine A improved learning and memory in mice better than tacrine. Unlike physostigmine and tacrine, Huperzine A acts specifically on AchE in the brain rather than AchE found elsewhere in the body�i.e., far less is wasted on irrelevant effects. Unlike physostigmine and tacrine, Huperzine A does not appear to bind to receptors in the central nervous system, which can cause adverse side effects. Its effects last 10 to 12 times longer than physostigmine and tacrine (up to 8 hours).

Huperzine is safe. Huperzine A is not known to be toxic even when administered at 50 to 100 times the human therapeutic dose. Approximately 10,000 people have been treated with Huperzine A with no evidence of toxicity.
FH-39-6 Huperzine A 60 Capsules $15.95
877-493-5987 U.S. Toll Free Order Line 9-6 Eastern
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References: Ashani Y, Peggins JO, Doctor BP. (1992) mechanism of inhibition of cholinesterase by huperzine A. Biochem Biophys Res Commun 184: 719-726. Carper, Jean. Your Miracle Brain, (2000) 292-294. Carper, Jean. Stop Aging Now! (1996) 150-157. Cheng DH, Ren H, Tang XC (1996) Huperzine A, a novel promising acetylcholinesterase inhibitor, Neuroreport 8: 97-101. Geib SJ, Tuckmantel W, Kozikowski AP (1991) Huperzine A�a potent acetylcholinesterase inhibitor of use in the treatment of Alzheimer�s disease. Acta Crystalogr C 47:824-827. Skolnick AA. Old Chinese herbal medicine used for fever yields possible new Alzheimer disease therapy. JAMA 1997 Mar 12;277(10):776. Zhang RW, Tang XC, Han YY et al. (1991) Drug evaluation of huperzine A in the treatment of senile memory disorders. Chung Kuo Yao Li Hsueh Pao 12: 250-252.

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